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The following additional unwanted effects have been observed with Simponi: Very common unwanted side effects (might affect more than 1 in 10 folks): Upper respiratory tract infections, sore throat or hoarseness, runny nose Common unwanted effects (could have an effect on as much as 1 in 10 folks): Abnormal liver exams (elevated liver enzymes) discovered throughout blood tests accomplished by your physician Feeling dizzy Headache Feeling numb or having a tingling feeling Superficial fungal infections Abscess Bacterial infections (corresponding to cellulitis) Low red blood cell counts Low white blood cell counts Positive blood lupus take a look at Allergic reactions Indigestion Stomach ache Feeling sick (nausea) Flu Bronchitis Sinus an infection Cold sores High blood stress Fever Asthma, shortness of breath, wheezing Stomach and bowel issues which include inflammation of the stomach lining and colon which may trigger fever Pain and ulcers in the mouth Injection web site reactions (together with redness, hardness, pain, bruising, itching, tingling and irritation) Hair loss Rash and itching of the skin Difficulty sleeping Depression Feeling weak Bone fractures Chest discomfort Uncommon unwanted effects (could affect as much as 1 in one hundred folks): Kidney an infection Cancers, together with skin most cancers and non-cancerous growths or lumps, together with pores and skin moles Skin blisters Severe infection all through the body (sepsis), typically including low blood pressure (septic shock) 186 Psoriasis (together with on the palms of your hand and/or the soles of your ft and/or in the type of pores and skin blisters) Low platelet count Combined low platelet, pink, and white blood cell count Thyroid problems Increase in blood sugar ranges Increase in blood cholesterol levels Balance issues Vision disturbances Inflamed eye (conjunctivitis) Eye allergy Sensation of heart beating irregularly Narrowing of the blood vessels within the coronary heart Blood clots Flushing Constipation Chronic inflammatory situation of the lungs Acid reflux Gall stones Liver problems Breast problems Menstrual issues Rare side effects (could affect up to 1 in 1,000 individuals): Failure of the bone marrow to produce blood cells Severely decreased number of white blood cells Infection of the joints or the tissue around them Impaired therapeutic Inflammation of blood vessels in internal organs Leukaemia Melanoma (a sort of skin cancer) Merkel cell carcinoma (a kind of pores and skin cancer) Lichenoid reactions (itchy reddish-purple pores and skin rash and/or threadlike white-gray strains on mucous membranes) Scaly, peeling skin Immune issues that would affect the lungs, pores and skin and lymph nodes (most commonly presenting as sarcoidosis) Pain and discolouration within the fingers or toes Taste disturbances Bladder issues Kidney disorders Inflammation of the blood vessels in your skin which results in rash Side results of which the frequency isn't known: A uncommon blood most cancers affecting principally younger people (hepatosplenic T-cell lymphoma) Worsening of a condition called dermatomyositis (seen as a pores and skin rash accompanying muscle weakness) Reporting of unwanted effects If you get any side effects, speak to your doctor, pharmacist or nurse. 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